
The ROBO Global Healthcare Technology and Innovation Index (HTEC) exhibited robust performance during the third quarter of 2024, registering a notable increase of 9.41%. This marks the index’s strongest performance of the year and the second-best since the second quarter of 2021.

Several factors contributed to the index’s exceptional growth. Firstly, a significant number of companies within the index surpassed analyst expectations for earnings per share (EPS), with an average beat of 22.35%. Secondly, the sector demonstrated overall strength, as 77% of companies reported positive year-over-year sales growth. Lastly, individual companies such as CareDx, Axogen, and Omnicell delivered exceptional gains, significantly boosting the index’s performance.
Diagnostics and Genomics Lead the Way

The diagnostics segment emerged as a standout performer, demonstrating a remarkable recovery from a challenging 2023. Exact Sciences played a pivotal role in this resurgence, exceeding expectations with its strong second-quarter adjusted earnings before interest, taxes, depreciation, and amortization (EBITDA). The company’s Cologuard product continued to drive significant revenue growth. Moreover, Exact Sciences’ announcement of promising data for a competitive blood test further solidified its position in the market.
The genomics segment also maintained its impressive momentum throughout 2024. CareDx led the charge, delivering a substantial increase of 91.9% during the quarter. This growth was supported by the company’s successful first-quarter performance and management’s upward revision of guidance for both revenue and losses. Additionally, Natera’s impressive volume growth for its Signatera product exceeded historical averages.
Key Developments and Mixed Signals
Beyond the diagnostics and genomics sectors, several other vital developments occurred during the quarter. Vertex Pharmaceuticals received FDA approval for a new, non-opioid pain medication, a significant breakthrough in the treatment of acute pain. In the robotics sector, Stryker’s acquisition of care.ai strengthened its capabilities in AI-powered healthcare IT solutions and wirelessly connected medical devices.
However, the medical instruments sub-segment faced challenges due to budget pressures. Dexcom experienced a significant decline following a poorly executed sales force restructuring. Nonetheless, the company remains optimistic about a turnaround by 2025 and has introduced the first over-the-counter continuous glucose monitoring system, presenting a promising market opportunity.
The precision medicine segment witnessed a reversal of fortunes for Moderna. The company’s stock price declined following reduced estimates and cuts to its research and development initiatives. Despite these setbacks, Moderna maintains a robust pipeline of products in respiratory diseases and aims for ten product approvals by 2027.
Cautiously Optimistic Outlook for 2025

While the overall outlook for 2025 remains cautiously optimistic, there are mixed signals emerging from the industry. Royal Philips reported normalized lead times across all modalities, indicating potential easing of supply chain pressures. However, Charles River’s management highlighted ongoing restructuring efforts within global biopharma companies, leading to pipeline prioritization and project cuts.
In conclusion, the ROBO Global Healthcare Technology and Innovation Index (HTEC) delivered a strong performance in the third quarter of 2024, driven by robust earnings growth, exceptional gains from individual companies, and the resurgence of diagnostics and genomics segments. While there are challenges and uncertainties ahead, the overall outlook for the healthcare technology sector remains positive. Investors may consider the HTEC index as a potential investment vehicle to capitalize on the growth and innovation within this dynamic industry.
VettaFi LLC (“VettaFi”) is the index provider for HTEC, for which it receives an index licensing fee. However, HTEC is not issued, sponsored, endorsed or sold by VettaFi, and VettaFi has no obligation or liability in connection with the issuance, administration, marketing, or trading of HTEC.
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